Figure 3From: The Ras guanine nucleotide exchange factor RasGRF1 promotes matrix metalloproteinase-3 production in rheumatoid arthritis synovial tissueRasGRF1 is expressed as a truncated protein in synovial tissue. Immunoblot analysis of Ras guanine nucleotide-releasing factor 1 (RasGRF1) and actin in rheumatoid arthritis (RA) and osteoarthritis (OA) synovial biopsy lysates. The 98 kDa, 75 kDa and 54 kDa proteins reacting with RasGRF1 antibodies, and the expected position of full-length 140 kDa RasGRF1, are indicated on the left by arrowheads. Relative mobility of molecular weight (Mw) standards (kDa) indicated to the right.Back to article page