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Table 5 Absolute numbers of B cells in bone marrow (per 106 mononuclear cells)

From: Short- and long-term effects of anti-CD20 treatment on B cell ontogeny in bone marrow of patients with rheumatoid arthritis

Long-term

CD27-IgD-

(Immature)

CD27-IgD+

(Naïve)

CD27+IgD+

(Unswitched)

CD27+IgD-

(Switched)

Total number of CD19+ cells

RTX-naïve

n = 24

185 ± 247

(32%)

206 ± 134

(36%)

35 ± 44

(6%)

148 ± 94

(26%)

574 ± 129

(100%)

RTX-treated

n = 13

260 ± 251

(51%)

P = ns

174 ± 147

(34%)

P = ns

4 ± 3

(1%)

P = 0.0009

68 ± 72

(13%)

P = 0.001

506 ± 118

(100%)

  1. * Values are given as mean ± standard deviation.
  2. ** Statistics are calculated with paired T-test, P-values are given in comparison to day 0.
  3. RTX = rituximab.