Short- and long-term effects of anti-CD20 treatment on B cell ontogeny in bone marrow of patients with rheumatoid arthritis

Table 6 Absolute numbers of B cells in bone marrow (per 10⁶ mononuclear cells)

Long-term	CD38+IgD- (Bm5)	CD38+IgD+ (Mature Bm2)	CD38++IgD- (Immature/T1)	CD38++IgD+ (Immature/T1)	CD38+++IgD- (Plasma blasts)
RTX-naïve n = 24	75 ± 54	205 ± 139	171 ± 258	39 ± 51	35 ± 26
RTX-treated n = 13	17 ± 19 P = 0.0004	155 ± 134 P = ns	222 ± 292 P = ns	19 ± 15 P = ns	22 ± 18 P = ns

* Values are given as mean ± standard deviation.
** Statistics are calculated with paired T-test, P-values are given in comparison to day 0.
RTX = rituximab.

ISSN: 1478-6362