Figure 2
From: Dichloroacetate alleviates development of collagen II-induced arthritis in female DBA/1 mice
Micrographs of tarsal joints from collagen II-immunized female and male DBA/1 mice. (a) Representative image of a tarsal joint from a female water-drinking mouse. (b) Representative image of a tarsal joint from a female dichloroacetate (DCA)-drinking mouse (3 mg DCA/mouse per day). (c) Representative image of a tarsal joint from a male water-drinking mouse. (d) Representative image of a tarsal joint from a male DCA-drinking mouse (3 mg DCA/day). Arrowheads indicate erosion of bone and cartilage. Scale bar = 100 μm. B: bone; C: cartilage; JC: joint cavity; S: synovitis.