|
Activity score
|
Week 1
|
Week 16
|
Week 28
|
Pvalue (95% confidence interval)
|
|---|
|
Skin
|
2.5 ± 0.5 (1 to 6)
|
1.2 ± 0.5 (0 to 4)
|
1.7 ± 0.5 (0 to 5)
|
0.01 (1.31 to 2.77)a
|
| | | | |
0.11 (-1.43 to -0.24)b
|
| | | | |
0.09 (-0.17 to 1.84)c
|
|
Osteitis
|
3.5 ± 0.4 (1 to 6)
|
1.9 ± 0.4 (0 to 4)
|
2.7 ± 0.5 (0 to 6)
|
0.01 (1.30 to 2.63)a
|
| | | | |
0.01 (-1.43 to -0.24)b
|
| | | | |
0.15 (-0.31 to 1.81)c
|
|
Erythrocyte sedimentation rate
|
24.8+-3.3 (9 to 45)
|
23.3+-2.8 (11 to 36)
|
25.7+-2.4 (12 to 40)
|
0.43 (-0.13 to 0.30)a
|
| | | | |
0.35 (-0.33 to 0.13)b
|
| | | | |
0.34 (-0.20 to 0.53)c
|
|
MRI
|
1.6 ± 0.1 (0 to 2)
|
1.2 ± 0.1 (0 to 2)
|
1.4 ± 0.2 (1 to 2)
|
0.01 (0.44 to 0.89)a
|
| | | | |
0.08 (-0.54 to 0.04)b
|
| | | | |
0.19 (-0.15 to 0.65)c
|
|
Health Assessment Score
|
3.8 ± 0.4 (2 to 6)
|
2.2 ± 0.3 (0 to 6)
|
3.3 ± 0.4 (1 to 6)
|
0.01 (1.51 to 2.79)a
|
| | | | |
0.02 (2.02 to 0.32)b
|
| | | | |
0.11 (-0.16 to 1.32)c
|
- Treatment finishing in week 16. Data presented as the mean ± standard error (range); n = 12. aPairwise test (value week 1 vs. value week 16). bPairwise test (value week 16 vs. value week 28). cPairwise test (value week 1 vs. value week 28).
