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Table 3 Predictive value for the progression from UA to RA within one year using the erosion score of the Sharp van der Heijde method with different cut-off values for erosions

From: The prognostic value of baseline erosions in undifferentiated arthritis

SHS erosion score

n

PPV

(95% CI)

NPV

(95% CI)

Specificity

(95% CI)

Sensitivity

(95% CI)

LR+

LR-

AUC (SEM)

≥1

148

45

37-53

75

70-79

77

73-82

42

34-50

1.9

0.75

0.60 (0.028)

≥2

92

51

41-61

73

69-78

87

84-91

29

22-36

2.3

0.80

0.58 (0.028)

≥3

61

52

40-65

72

68-76

92

89-95

20

14-26

2.5

0.87

0.56 (0.028)

≥4

39

56

41-72

71

67-75

95

93-98

14

8-19

2.9

0.90

0.55 (0.028)

≥5

23

61

41-81

71

67-75

97

96-99

9

4-13

3.5

0.94

0.53 (0.028)

  1. n = number of UA patients positive for this cutoff.
  2. AUC = area under the curve; CI = confidence interval; LR+ = positive likelihood ratio; LR- = negative likelihood ratio; NPV = negative predictive value; PPV = positive predictive value; RA = rheumatoid arthritis; SEM = standard error of measurement; SHS = Sharp/van der Heijde scoring; UA = undifferentiated arthritis.