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Figure 1 | Arthritis Research & Therapy

Figure 1

From: Effect of small interference RNA (siRNA) for ADAMTS5on intervertebral disc degeneration in the rabbit anular needle-puncture model

Figure 1

Establishment of small interfering RNA (siRNA) oligonucleotide for ADAMTS5 in rabbit nucleus pulposus (NP) cells. After the 48-hour preculture period, rabbit NP cells were transfected with the siRNA oligonucleotide specific for either the control or ADAMTS5. At 48 hours after transfection in NP cells, the ADAMTS5 siRNA-transfected cells showed approximately a 75% knock-down of ADAMTS5 mRNA compared with the control siRNA. The results are reported normalized to glyceraldehyde 3-phosphate dehydrogenase (GAPDH).

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