Figure 1From: Connective tissue growth factor promotes articular damage by increased osteoclastogenesis in patients with rheumatoid arthritisThe serum levels of connective tissue growth factor in patients with rheumatoid arthritis. The serum concentration of connective tissue growth factor (CTGF) in patients with RA (n = 39), SLE and SS (n = 15) and normal healthy controls (n = 50) were measured using a sandwich ELISA (Figure 1A). Dotted line (Figure 1A) indicates the cut off point designed as the mean OD + 3 SD for normal sera. Value above the cut off point was defined as an elevated serum CTGF concentration. Comparison of the serum concentrations of CTGF between active (n = 20) and inactive (n = 19) RA patient was shown (Figure 1B). Comparison of the serum concentrations of CTGF between before and after Infliximab treatment was also shown (Figure 1C). The sera treated with infliximab (n = 10) were collected at post 24 hrs after the first administration. Bars in 1B and 1C indicate the SD.Back to article page