Total cholesterol and triglycerides are associated with the development of new bone marrow lesions in asymptomatic middle-aged women - a prospective cohort study

Table 2 Association between bone marrow lesions at baseline and lipids

	Univariate analysis, odds ratio (95% CI)	Pvalue	Multivariate analysis, odds ratio (95% CI)^a	Pvalue
Total cholesterol	0.91 (0.62, 1.33)	0.63	0.9 (0.6,1.35)	0.61
Ln triglycerides	1.99 (0.77, 5.16)	0.15	1.81 (0.63, 5.20)	0.27
Ln HDL	0.45 (0.09, 2.12)	0.31	0.63 (0.11, 3.50)	0.6
Ln LDL	0.65 (0.15, 2.90)	0.58	0.58 (0.12, 2.80)	0.50
Total/HDL ratio	1.10 (0.81, 1.50)	0.54	1.03 (0.73, 1.43)	0.88

^aOdds ratio of having a bone marrow lesion present at baseline for each unit increase in total cholesterol, natural logarithm (Ln) of triglycerides, natural logarithm of high-density lipoprotein (HDL) or low-density lipoprotein (LDL) or for the total/HDL ration after adjusting for age and body mass index. CI, confidence interval.

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