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Figure 2 | Arthritis Research & Therapy

Figure 2

From: Expression of semaphorin 3A and its receptors in the human intervertebral disc: potential role in regulating neural ingrowth in the degenerate intervertebral disc

Figure 2

Immunohistochemical localisation of sema3A in the healthy and degenerate disc. (a) Healthy outer annulus fibrosus with cells demonstrating immunopositivity for sema3A with approximately 80% of the elongated AF cells being positive. Arrows highlight negative AF cells. (b) Degenerate NP demonstrating immunopositivity in the majority of chondrocyte-like cell clusters. (c) OAF in severely degenerate disc demonstrating a low immunopositivity. Arrows highlight positive AF cells. (d) Healthy OAF with the sema3A antibody omitted used as a negative control.

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Arthritis Research & Therapy

ISSN: 1478-6362

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