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Figure 1 | Arthritis Research & Therapy

Figure 1

From: A Rac1 inhibitory peptide suppresses antibody production and paw swelling in the murine collagen-induced arthritis model of rheumatoid arthritis

Figure 1

The Rac1 carboxy-terminal peptide efficiently blocks actin polymerization in murine cells. (a) Representative histograms of F-actin staining in T cells isolated from mice spleens that were exposed for 15 minutes to 200 μg/mL of Ctrl or Rac1 peptide followed by stromal cell-derived factor 1 (SDF-1) stimulation. (b) Fold increase in F-actin. Data are depicted as mean fold increase (MFI) of F-actin ± standard error of the mean (n = 3). *P < 0.05. Ctrl, control.

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