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Table 1 Characteristics of participants

From: Development of bone marrow lesions is associated with adverse effects on knee cartilage while resolution is associated with improvement - a potential target for prevention of knee osteoarthritis: a longitudinal study

  With BMLs at baseline
(n = 37)
Free of BMLs at baseline
(n = 234)
  BMLs persisted
(n = 20)
BMLs resolved
(n = 17)
Pvalue BMLs developed
(n = 33)
No BMLs developed
(n = 201)
Pvalue
Age (years) 58.6 (5.5) 57.8 (6.4) 0.701 57.7 (5.9) 57.8 (5.0) 0.901
Gender (% female) 13 (65%) 11 (65%) 0.982 23 (70%) 122 (61%) 0.302
Body mass index (kg/m2) 25.9 (3.9) 24.8 (4.1) 0.501 28.0 (5.1) 25.4 (3.7) 0.011
Annual change in cartilage volume (μl)       
   Medial tibial 36.0 (39.2) 10.5 (45.9) 0.131 34.0 (54.6) 19.5 (50.0) 0.081
   Lateral tibial 25.6 (67.2) 28.4 (42.1) 0.081 37.6 (57.0) 21.0 (48.4) 0.881
Progression of tibiofemoral cartilage defects, number (%)       
   Medial 7 (35%) 3 (18%) 0.152 11 (33%) 44 (21%) 0.242
   Lateral 9 (18%) 8 (47%) 0.0082 15 (45%) 47 (23%) 0.902
  1. Mean (standard deviation) unless otherwise stated. BML = bone marrow lesion.
  2. 1 Independent samples t-test
  3. 2 Chi-squared test