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Figure 1 | Arthritis Research & Therapy

Figure 1

From: IL-17 derived from juxta-articular bone and synovium contributes to joint degradation in rheumatoid arthritis

Figure 1

Effect of exogenous IL-17 on IL-6 production by RA synovium. Synovium samples from RA patients were incubated for 7 days in the presence of IL-17 (50 ng/ml; n = 10), IL-1 (100 pg/ml; n = 10), and IL-17 + IL-1 (n = 3). ELISA measured IL-6 levels in supernatants. Results are expressed as mean ± SEM of % induction of IL-6 production. Spontaneous production of IL-6 was 202 ± 57 ng/ml. *P < 0.01, **P < 0.05 compared with control (medium alone).

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