Skip to main content
Figure 4 | Arthritis Research & Therapy

Figure 4

From: IL-17 derived from juxta-articular bone and synovium contributes to joint degradation in rheumatoid arthritis

Figure 4

Effect of exogenous IL-17 on IL-6 production by RA bone explants. Bone samples from RA patients were incubated for 7 days in the presence of IL-17 (50 ng/ml; n = 5), IL-1 (100 pg/ml; n = 5), and IL-17 + IL-1 (n = 2). ELISA measured IL-6 levels in supernatants. Results are expressed as mean ± SEM of % induction of IL-6 production. Spontaneous production of IL-6 was 220 ± 95 ng/ml. *P < 0.05 compared with control (medium alone).

Back to article page

Arthritis Research & Therapy

ISSN: 1478-6362

Contact us