Skip to main content

Table 1 Annualized lifetime rates of progression and levels of disability and health status in rheumatoid arthritis

From: The loss of health status in rheumatoid arthritis and the effect of biologic therapy: a longitudinal observational study

Variable All patients
(N = 18,485)
Rate of progression
Rate (95% CI)
Values at RA duration
Of 0 years (onset)*
Mean (95% CI)
Values at RA duration of 10 years*
Mean (95% CI)
Values at RA duration of 20 years
Mean (95% CI)
HAQ 0.016 (0.015, 0.017) 0.84 (0.83, 0.86) 1.00 (0.99, 1.01) 1.16 (1.15, 1.18)
PCS -0.125 (-0.142, -0.108) 37.9 (37.6, 38.1) 36.6 (36.5, 36.8) 35.4 (35.2, 35.6)
MCS 0.047 (0.031, 0.063) 48.5 (48.3, 48.8) 49.0 (48.8, 49.1) 49.4 (49.4, 49.6)
EQ-5D -0.001 (-0.001, -0.000) 0.748 (0.742, 0.754) 0.739 (0.736, 0.743) 0.731 (0.727, 0.735)
  1. Positive rates indicate worsening HAQ disability. Negative rates indicate worsening health status for MCS, PCS, and EQ-5D. Values at 0, 10, and 20 years RA duration are estimated from the mixed model regression analysis.
  2. HAQ, Health Assessment Questionnaire; PCS, SF-36 Physical Component Summary; MCS, SF-36 Mental Component Summary.