Diagnostic value of anti-cyclic citrullinated peptides and association with HLA-DRB1 shared epitope alleles in African rheumatoid arthritis patients

Table 4 Role of the shared epitope as predictor of the presence of ACPA and RF in RA patients

SE (1 or 2 copies)	IgM RF		IgA RF		anti-CCP2		anti-CCP3
	pos	neg	pos	neg	pos	neg	pos	neg
0	29	10	32	7	30	9	30	9
1	14	3	15	2	16	1	16	1
	P = 0.73		P = 0.71		P = 0.25		P = 0.12

Patients with RA were separated according to the presence (1) or absence (0) of one or two copies of the shared epitope (SE) and the presence (pos) or absence (neg) of IgM rheumatoid factor (RF), IgA RF, anti-cyclic citrullinated peptides (CCP)2, anti-CCP3. The statistical analysis was performed by using Fisher's exact

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