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Table 4 Role of the shared epitope as predictor of the presence of ACPA and RF in RA patients

From: Diagnostic value of anti-cyclic citrullinated peptides and association with HLA-DRB1 shared epitope alleles in African rheumatoid arthritis patients

SE (1 or 2 copies) IgM RF IgA RF anti-CCP2 anti-CCP3
  pos neg pos neg pos neg pos neg
0 29 10 32 7 30 9 30 9
1 14 3 15 2 16 1 16 1
  P = 0.73 P = 0.71 P = 0.25 P = 0.12
  1. Patients with RA were separated according to the presence (1) or absence (0) of one or two copies of the shared epitope (SE) and the presence (pos) or absence (neg) of IgM rheumatoid factor (RF), IgA RF, anti-cyclic citrullinated peptides (CCP)2, anti-CCP3. The statistical analysis was performed by using Fisher's exact