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Table 1 First symptom by disease category.

From: Anticentromere antibody positive Sjögren's Syndrome: a retrospective descriptive analysis

First symptom Disease category
  ACA+/SS
(n = 20) [%]
SSc/(-) sicca
(n = 20) [%]
SSc/(+) sicca
(n = 31) [%]
ACA-/SS
(n = 61) [%]
Raynaud phenomenon 6 [30.00] 18 [90.00] 29 [93.55] 5 [8.20]
sicca manifestations 15 [75.00] - 6 [19.35] 52 [85.25]
SGE 1 [5.00] - 1 [3.23] 12 [19.67]
arthritis 1 [5.00] 1 [5.00] 2 [6.45] 4 [6.56]
purpura, - - - 4 [6.56]
puffy fingers/sclerodactyly 1 [5.00] 6 [30.00] 8 [25.81] 4 [6.56]
digital ulcers - 2 [10.00] 1 [3.23] -
dysphagia/GER 1 [5.00] 1 [5.00] 1 [3.23] -
lung fibrosis - - - 1 [1.64]
  1. Some patients reported more than one initial symptom. SGE, salivary gland enlargement, GER, gastroesophageal reflux