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Figure 3 | Arthritis Research & Therapy

Figure 3

From: Platelet-derived growth factor and transforming growth factor beta synergistically potentiate inflammatory mediator synthesis by fibroblast-like synoviocytes

Figure 3

Reversal by imatinib (1 μM) of 2GF potentiation of TNFα-induced (a) IL6, (b) IL8, (c) MIP1α, and (d) MMP3 secretion. For culture conditions and definitions, see legends for Figure 1 and 2. Supernatants were analyzed by ELISA or Luminex multiplex bead assay. Mean & SEM, n = 3 RA FLS lines. Asterisk indicates P < 0.05 to vehicle by Students' t-test.

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Arthritis Research & Therapy

ISSN: 1478-6362

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