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Table 1 Demographics, laboratory, and clinical characteristics of subjects

From: Monocyte surface expression of Fcγ receptor RI (CD64), a biomarker reflecting type-I interferon levels in systemic lupus erythematosus

 

Controls

(n = 83)

SLE

(n = 108)

Demographics

  

   Female (%)

93

94

   Mean age (years)

36

38

   Race/ethnicity (%)

  

African-American

35

36

White

32

40

Others

33

24

   Disease duration (years)

-

12.1 ± 0.7

   ACR criteria (mean)

-

6.2 ± 0.2

Serum markers

  

   C3 (mg/dL)

123.4 ± 5.7

95.4 ± 5.5

   C4 (mg/dL)

25.7 ± 3.5

19.7 ± 1.5

   hsCRP (mg/dL)

1.4 [1.1-4.4]

5.7 [4.1-7.1]

SLE manifestationsa(%)

  

   CNS

-

18

   Skin

-

63

   Joint

-

84

   Serositis

-

34

   Anti-dsDNA

-

61

   Anti-Sm

-

45

   Anti-phospholipid

-

50

Medication use (%)

  

Prednisone

-

51

   Mean dose (mg/day)

 

15.5

Antimalarials

-

70

Cytotoxic agentsb

-

21

Statins

-

18

ACE inhibitors

-

48

  1. aPresence of specific manifestations at any point during the course of disease.
  2. bCytotoxic agents included cyclophosphamide, mofetil mycophenolate, azathioprine, and methotrexate.
  3. ACR, American College of Rheumatology; C3, C4, complement 3 and complement 4; hs-CRP, high sensitivity C-reactive protein; SLE, systemic lupus erythematosus.