|
Univariate1
|
Multivariate2
|
---|
Variable
|
Beta (β)
|
P value
|
HR (95%CI)
|
Beta (β)
|
P value
|
HR (95%CI)
|
---|
RF positive
|
0.114
|
0.328
|
1.121 (0.892-1.408)
| | | |
Male gender
|
-0.641
|
0.000
|
0.527 (0.433-0.641)
|
-0.511
|
0.000
|
0.600 (0.469-0.767)
|
Age
|
-0.009
|
0.008
|
0.991 (0.984-0.998)
|
-0.007
|
0.047
|
0.993 (0.986-0.999)
|
Baseline DAS
|
-0.364
|
0.000
|
0.695 (0.635-0.760)
|
-0.693
|
0.000
|
0.500 (0.434-0.576)
|
Baseline HAQ
|
-0.436
|
0.000
|
0.647 (0.529-0.791)
| | | |
Dis duration
|
-0.005
|
0.217
|
0.995 (0.987-1.003)
| | | |
44 SJC
|
-0.018
|
0.007
|
0.982 (0.969-0.995)
| | | |
53 TJC
|
-0.057
|
0.000
|
0.945 (0.932-0.958)
| | | |
ESR
|
-0.004
|
0.048
|
0.996 (0.992-0.999)
| | | |
VAS GH
|
-0.017
|
0.000
|
0.983 (0.978-0.987)
| | | |
- 1 Results of univariate Cox proportional hazard models with baseline predictors for time-to-DAS remission (disease activity score, DAS<1.6) up to three years of follow-up, given with hazard ratios (HR) and 95% confidence intervals (95%CI). 2 Results of the final multivariate Cox proportional hazard prediction model with independent baseline predictors for the time-to-remission (disease activity score, DAS<1.6) up to three years of follow-up, given with hazard ratios (HR) and 95% confidence intervals (95%CI).
- RF = rheumatoid factor; DAS = disease activity score based on 53 tender joint counts (TJC) and 44 swollen joint counts (SJC); HAQ = health assessment questionnaire; Dis = disease; ESR = erythrocyte sedimentation rate; VAS = visual analogue scale; GH = general health. Age was measured in years and disease duration in weeks.