Skip to main content

Table 1 Proliferation of chondrocytes isolated and cultured at 280 mOsm, 380 mOsm and 480 mOsm

From: Physiological tonicity improves human chondrogenic marker expression through nuclear factor of activated T-cells 5 in vitro

  Chondrocyte proliferation (%)
Culture condition Passage 0 Passage 1 Passage 2 Passage 3
280 mOsm 100 (68 ± 28 hours) 100 (89 ± 54 hours) 100 (67 ± 48 hours) 100 (57 ± 11 hours)
380 mOsm 113 ± 18 89 ± 25 99 ± 9 154 ± 41
480 mOsm 675 ± 405* 180 ± 24* 168 ± 28* 165 ± 81*
  1. Data presented as relative doubling times in percentage of cells cultured at 280 mOsm, mean ± standard deviation. The absolute doubling time ± standard deviation in hours is displayed in brackets. n = 6. mOsm, milliosmoles per kilogram of water. *P < 0.05.