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Table 2 Receiver operator characteristics for individual reported pulmonary symptoms to predict the presence of PFT abnormalities

From: Respiratory symptoms and disease characteristics as predictors of pulmonary function abnormalities in patients with rheumatoid arthritis: an observational cohort study

Pulmonary symptom Any PFT abnormalitya Restrictiona Obstructiona Impaired diffusiona
  AUC 95% CIb AUC 95% CIb AUC 95% CIb AUC 95% CIb
Cough         
   Frequentc 0.60 (0.53 to 0.67)d -   -   0.61 (0.53 to 0.70)
   Morning 0.57 (0.50 to 0.64) -   0.62 (0.51 to 0.74) 0.65 (0.56 to 0.74)d
   Daytime or night 0.57 (0.50 to 0.66) -   -   0.59 (0.51 to 0.68)
   Chronice -   -   0.62 (0.51 to 0.75)d 0.61 (0.52 to 0.71)
Phlegm         
   Frequentc -   -   -   0.59 (0.52 to 0.67)
   Morning -   -   -   0.60 (0.52 to 0.70)
   Daytime or night 0.57 (0.51 to 0.63) -   -   0.61 (0.53 to 0.70)
   Chronice 0.59 (0.53 to 0.67)d -   -   0.66 (0.58 to 0.75)d
Wheezing         
   Any 0.58 (0.53 to 0.65) -   0.63 (0.51 to 0.76)d 0.62 (0.53 to 0.73)d
   Oftenf 0.63 (0.56 to 0.71)d -   -   -  
Breathlessness         
   Hurrying or walking on incline 0.56 (0.51 to 0.63) 0.66 (0.51 to 0.80) -   0.60 (0.51 to 0.70)d
   With level walking at own pace 0.57 (0.51 to 0.64) 0.66 (0.51 to 0.81)d -   0.59 (0.50 to 0.67)
   After 100 yards of level walking 0.60 (0.52 to 0.67)d    -   -  
  1. PFT, pulmonary function test. aAreas under the curve (AUCs) are reported only for internally valid models; that is, those in which the 95% confidence interval (CI) did not include 0.5 (uninformative). b95% CI obtained with repeated sampling and calculation of the AUC for 1, 000 bootstrap resamples with replacement. cDefined as much as four to six times per day, 4 days or more per week. dSymptoms selected for inclusion in subsequent multivariable modeling. eDefined as on most days for at least 3 consecutive months per year. fDefined as on most days or nights.