Tumor necrosis factor and norepinephrine lower the levels of human neutrophil peptides 1-3 secretion by mixed synovial tissue cultures in osteoarthritis and rheumatoid arthritis

Table 1 Patient characteristics

	Osteoarthritis	Rheumatoid arthritis
Number	10	7
Age (years)	62.8 ± 3.2	57.0 ± 4.0
Sex (f/m)	6/4	4/3
C-reactive protein (mg/L)	5.1 ± 1.3	25.9 ± 14.1^#
Erythrocyte sedimentation rate (mm)	11.5 ± 1.5	27.6 ± 3.1*
Lining layer thickness, cells	2.0 ± 0.5	2.5 ± 0.2
Cellular density (all cells), cells/mm²	364 ± 169	635 ± 329
T-cell density, cells/mm²	1.1 ± 0.1	1.9 ± 0.5
Macrophage density, cells/mm²	55 ± 38	52 ± 16
Medication
Prednisolone (%)	N.A.	86.0
Daily prednisolone (mg/day)	N.A.	6.1 ± 1.7
Methotrexate (%)	N.A.	71.0
Leflunomide (%)	N.A.	14.0
Nonsteroidal antiinflammatory drugs (%)	70.0	71.0

Data are given as mean ± SEM. *P < 0.05; ^#P < 0.005 for the comparison with osteoarthritis. Abbreviations: N.A., not applicable.

ISSN: 1478-6362