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Table 3 Infusion-related events and symptoms

From: 74-week follow-up of safety of infliximab in patients with refractory rheumatoid arthritis

  Week 0 to 6 Week 7 to 26 Week 27 to 50 Week 51 to 74 Total
Infusion-related eventsa 23 28 15 11 77
Symptom      
   Allergic skin reaction 2 13 6 3 24
   Hemodynamic events (hypotension, syncope, bradycardia, cyanosis) 4 8 2 2 16
   Hyperventilation/dyspnea 1 5 5 2 13
   Flushing 0 4 2 1 7
   Hypertension 2 3 0 1 6
   Tachycardia/palpitation 2 2 1 0 5
   Headache 1 1 1 1 4
   Throat, Quincke's, or mouth edema 0 2 1 0 3
   Polyathralgia 2 0 0 1 3
   Limb edema 1 1 0 0 2
   Flu-like symptom 2 0 0 0 2
   Allergic reaction, unspecified 1 0 0 0 1
   Other 9 8 5 4 26
  1. a Each infusion reactions could result in multiple symptoms so that the total number of symptoms (n = 112) exceeded the number of infusion-related events (n = 77).