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Table 3 Infusion-related events and symptoms

From: 74-week follow-up of safety of infliximab in patients with refractory rheumatoid arthritis

 

Week 0 to 6

Week 7 to 26

Week 27 to 50

Week 51 to 74

Total

Infusion-related eventsa

23

28

15

11

77

Symptom

     

   Allergic skin reaction

2

13

6

3

24

   Hemodynamic events (hypotension, syncope, bradycardia, cyanosis)

4

8

2

2

16

   Hyperventilation/dyspnea

1

5

5

2

13

   Flushing

0

4

2

1

7

   Hypertension

2

3

0

1

6

   Tachycardia/palpitation

2

2

1

0

5

   Headache

1

1

1

1

4

   Throat, Quincke's, or mouth edema

0

2

1

0

3

   Polyathralgia

2

0

0

1

3

   Limb edema

1

1

0

0

2

   Flu-like symptom

2

0

0

0

2

   Allergic reaction, unspecified

1

0

0

0

1

   Other

9

8

5

4

26

  1. a Each infusion reactions could result in multiple symptoms so that the total number of symptoms (n = 112) exceeded the number of infusion-related events (n = 77).