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Figure 5 | Arthritis Research & Therapy

Figure 5

From: Immature cell populations and an erythropoiesis gene-expression signature in systemic juvenile idiopathic arthritis: implications for pathogenesis

Figure 5

Bone marrow biopsy from a patient with new-onset systemic JIA. (a) H&E staining showing hypercellular bone marrow with prominent accumulations of nucleated erythroblasts (arrows). (b) Immunostaining with monoclonal antibodies specific for CD163. Brown staining identifies CD163+ cells (some are hemophagocytic). CD163+ macrophages are very rare in a normal bone marrow (not shown).

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