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Table 6 Functional enrichment in gene categories in patients with skin ulcers compared to those without ulcers

From: Gene expression profiling in circulating endothelial cells from systemic sclerosis patients shows an altered control of apoptosis and angiogenesis that is modified by iloprost infusion

Biological process Number of probe sets P-value
Immune response 210 0.0000000009
Defense response 221 0.0000000145
Response to wounding 109 0.0000012730
Signal transducer activity 472 0.0000206037
Response to stress 236 0.0000215677
Regulation of cell proliferation 89 0.0000403309
Positive regulation of nitric oxide biosynthesis 8 0.0001150065
Positive regulation of biosynthesis 16 0.0001813324
Receptor activity 290 0.0003570920
Cell activation 36 0.0005153290
Cell proliferation 137 0.001020579
Positive regulation of innate immune response 3 0.001302911
Regulation of immune response 27 0.001521656
Inflammatory response 47 0.002011958
Positive regulation of immune response 20 0.002900865
Cell adhesion 136 0.006908177
Cytokine activity 47 0.017808983