Results of Western blot analysis for nuclear class I HDACs protein expressions in synovial tissues. (a) Class I HDACs (HDAC1, 2, 3, 8) protein expressions in synovial tissues that were obtained from osteoarthritis (OA, n = 3) and rheumatoid arthritis (RA, n = 3) synovial tissues. Lamin A, nuclear membrane protein, served as loading control. (b) Densitometric analysis class I HDACs protein in OA and RA synovial tissue was The data were plotted as means ± SE. * = P < 0.05 versus OA.