TLR4, TLR7 and TLR9 expression on HD and SLE pDCs + apoPMNs. HD (n = 5) pDCs + apoPMNs showed a significant increase in the expression of TLR9 mRNA (c) while SLE (n = 5) pDCs + apoPMNs did not. No significant changes in TLR4 (a) and TLR7 (b) expression were found in either HD or SLE pDCs + apoPMNs. Values are expressed in Median (interquartile range, range). pDCs + apoPMNs, pDCs that had been loaded with apoptotic polymorphonuclear cells; HD, healthy donors.