Table 1 Characteristics of study population (n = 142)

Age (yr)

41.7 ± 5.3^a

Height (cm)

163.6 ± 5.8^a

Weight (kg)

   baseline

66.9 ± 14.1^a

   current

73.0 ± 16.7^a

   change

4.6 (0.9 to 11.1)^b

Body mass index (kg/m²)

   baseline

25.0 ± 5.0^a

   current

27.3 ± 6.3^a

   change

1.8 (0.3 to 4.2)^b

Any significant tibiofemoral cartilage defect, number = (%)

76 (53.5%)^c

Tibial cartilage volume (ml)

23.1 ± 3.9^a

Tibial plateau bone area (cm²)

30.2 ± 2.4^a

Presence of bone marrow lesions, number = (%)

9 (6.3%)^c

Osteophytes, number = (%)

13 (9.2%)