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Table 1 Baseline characteristics of the study cohort 12 months prior to the index date

From: Risk of osteoporotic fracture in a large population-based cohort of patients with rheumatoid arthritis

  RA patients
(n= 47,034)
Non-RA patients§
(n= 235,170)
Demographic   
   Age, years 55 (46-64) 55 (46-64)
   Sex, female 34,169 (73) 170,845 (73)
Osteoporosis-related   
   Osteoporosis diagnosis 8,385 (18) 16,724 (7)
   Osteoporosis medication 5,634 (12) 14,067 (6)
   Prior fracture 413 (0.9) 1,322 (0.6)
   Bone mineral density test 5,802 (12) 13,307 (6)
   Parkinson's disease 177 (0.4) 718 (0.3)
   Alzheimer's disease 156 (0.3) 752 (0.3)
   Prior fall 609 (1) 2351 (1)
   At least one comorbidity 39,259 (83) 53,299 (23)
   Comorbidity index * 1 (1-2) 0 (0-0)
   CIRAS score 5.2 (3.7-6.9) 3.6 (2.9-4.3)
Medication use   
   Oral glucocorticoids 18,222 (39) 15,342 (7)
   Anticonvulsants 3,703 (8) 7,795 (3)
   Benzodiazepines 8,362 (18) 25,754 (11)
   SSRIs 7,289 (16) 22,920 (10)
   Beta-blockers 6,520 (14) 25,166 (11)
   Proton pump inhibitors 9,415 (20) 19,859 (8)
   Opioids 22,049 (47) 54,204 (23)
Health care utilization   
   Number of physician visits 8 (5-14) 2 (0-6)
   Hospitalizations 8,894 (19) 25,131(11)
   Number of all prescription drugs 8 (4-13) 3 (0-7)
  1. Data are expressed as number (%) or median (interquartile range); § 1:5 matched on age and sex. *, Charlson-Deyo Comorbidity Index [33]; a score of 0 represents absence of comorbidity and higher scores indicate a greater burden of comorbidity.
  2. CIRAS, Claims-based Index for RA Severity; RA, rheumatoid arthritis; SSRI, selective serotonin reuptake inhibitor.