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Table 4 Best-fit models for cartilage and bone destruction predicted by both scoring methods and serum markers

From: A multiparameter approach to monitor disease activity in collagen-induced arthritis

Dependent variable Best-fit model Adjusted R2 Significance
Cartilage destruction Larsen score 0.530 < 0.001
  Larsen score + micro-CT calcaneus score 0.664 < 0.001
  Larsen score + micro-CT calcaneus score + clinical score 0.700 < 0.001
Bone destruction Micro-CT calcaneus score 0.602 < 0.001
  Micro-CT calcaneus score + Larsen score 0.711 < 0.001
  Micro-CT calcaneus score + Larsen score + COMP 0.731 < 0.001
  1. Best-fit models for cartilage and bone destruction in the paw as proposed by linear regression analysis with all scoring methods and serum markers and treatment group as independent variables. COMP, cartilage oligomeric matrix protein.