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Table 2 Heritability estimates for radiographic phenotypes, after adjustment for age, gender and body mass index

From: Heritability patterns in hand osteoarthritis: the role of osteophytes

  All subjects Caucasians only
Phenotype Heritability estimate (SE) Pvalue Heritability estimate (SE) Pvalue
First IP count 0.63 (0.15) 0.00004 0.70 (0.15) 0.00001
DIP count 0.36 (0.1643) 0.02 0.36 (0.17) 0.019
PIP counta 0.30 (0.16) 0.03 0.28 (0.17) 0.04
DIP/IP/PIP counta 0.42 (0.16) 0.004 0.41 (0.16) 0.006
CMC count 0.38 (0.17) 0.01 0.46 (0.17) 0.005
Total counta 0.38 (0.16) 0.008 0.38 (0.16) 0.01
First IP scorea 0.84 (0.14) 0.0000001 0.89 (0.14) 2.70 × 10-9
DIP scorea 0.18 (0.16) 0.12 0.16 (0.17) 0.17
PIP scorea 0.16 (0.15) 0.15 0.14 (0.16) 0.18
DIP/IP/PIP scorea 0.33 (0.16) 0.02 0.33 (0.16) 0.02
CMC score 0.53 (0.16) 0.0006 0.63 (0.16) 0.0001
Total scorea 0.35 (0.16) 0.01 0.36 (0.16) 0.01
Subchondral cystsa 0.17 (0.15) 0.13 0.13 (0.16) 0.20
Joint subluxationa 0.27 (0.17) 0.06 0.19 (0.19) 0.15
Joint space narrowinga 0.24 (0.16) 0.06 0.18 (0.17) 0.14
Subchondral sclerosisa 0.17 (0.16) 0.14 0.15 (0.17) 0.18
Erosionsa 0.12 (0.14) 0.20 0.13 (0.15) 0.20
Joint deformitya 0.31 (0.20) 0.06 0.15 (0.20) 0.24
Heberden's nodes 0.36 (0.22) 0.07 0.21 (0.23) 0.19
  1. CMC, carpometacarpal joint; DIP, distal interphalangeal joint; IP, interphalangeal joint; PIP, proximal interphalangeal joint; SE, standard error. aTransformed by square root. Statistically significant results are represented in bold.