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Table 3 Univariate and multivariate linear regression analysis for SAE in SLE patients and healthy controls (CTL)

From: Small artery elasticity is decreased in patients with systemic lupus erythematosus without increased intima media thickness

  Univariate analysis Multivariate analysis (R2= 0.524)
  B (95% CI) P-value B (95% CI) P-value
Age (yr) -0.119 (-0.182 to -0.056) < 0.001 -0.126 (-0.178 to 0.074) < 0.001
Gendera -2.357 (-4.392 to -0.323) 0.024 -2.067 (-3.656 to -0.477) 0.012
BMI (kg/m2) 0.092 (-0.094 to -0.278) 0.324 **  
Blood pressure (mmHg)     
   Systolic -0.019 (-0.073 to 0.035) 0.486 **  
   Diastolic -0.065 (-0.154 to 0.024) 0.151 **  
Antihypertensives useb 0.201 (-1.636 to 2.037) 0.828 *  
Dyslipidaemiac -0.645 (-2.106 to 0.816) 0.381 **  
Smokingd -2.542 (-4.240 to -0.844) 0.004 -2.186 (-3.589 to -0.782) 0.003
Family history CVDe 0.667 (-1.285 to 2.619) 0.497 **  
HbA1c -0.597 (-2.895 to 1.702) 0.596 **  
SLE or CTLf -0.916 (-1552 to -0.279) 0.005 -1.425 (-2.549 to - 0.301) 0.014
  1. B refers to influence on SAE.
  2. * Variable was not selected during multivariate regression analysis.
  3. **Variable was not tested in multivariate regression analysis because of a P-value > 0.05 in univariate regression analysis and/or no significant difference between between healthy controls and SLE patients.
  4. a: male were defined as 0, female as 1, b: non-hypertensive subjects were defined as 0, hypertentive subjects as 1, c: no dyslipidaemia was defined as 0, dyslipidaemia as 1, d: non-smokers were defined as 0, smokers as 1, e: negative family history was defined as 0, positive family as 1, f: healthy controls were defined as 0, SLE patients were defined as 1.