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Table 3 Univariate and multivariate linear regression analysis for SAE in SLE patients and healthy controls (CTL)

From: Small artery elasticity is decreased in patients with systemic lupus erythematosus without increased intima media thickness

 

Univariate analysis

Multivariate analysis (R2= 0.524)

 

B (95% CI)

P-value

B (95% CI)

P-value

Age (yr)

-0.119 (-0.182 to -0.056)

< 0.001

-0.126 (-0.178 to 0.074)

< 0.001

Gendera

-2.357 (-4.392 to -0.323)

0.024

-2.067 (-3.656 to -0.477)

0.012

BMI (kg/m2)

0.092 (-0.094 to -0.278)

0.324

**

 

Blood pressure (mmHg)

    

   Systolic

-0.019 (-0.073 to 0.035)

0.486

**

 

   Diastolic

-0.065 (-0.154 to 0.024)

0.151

**

 

Antihypertensives useb

0.201 (-1.636 to 2.037)

0.828

*

 

Dyslipidaemiac

-0.645 (-2.106 to 0.816)

0.381

**

 

Smokingd

-2.542 (-4.240 to -0.844)

0.004

-2.186 (-3.589 to -0.782)

0.003

Family history CVDe

0.667 (-1.285 to 2.619)

0.497

**

 

HbA1c

-0.597 (-2.895 to 1.702)

0.596

**

 

SLE or CTLf

-0.916 (-1552 to -0.279)

0.005

-1.425 (-2.549 to - 0.301)

0.014

  1. B refers to influence on SAE.
  2. * Variable was not selected during multivariate regression analysis.
  3. **Variable was not tested in multivariate regression analysis because of a P-value > 0.05 in univariate regression analysis and/or no significant difference between between healthy controls and SLE patients.
  4. a: male were defined as 0, female as 1, b: non-hypertensive subjects were defined as 0, hypertentive subjects as 1, c: no dyslipidaemia was defined as 0, dyslipidaemia as 1, d: non-smokers were defined as 0, smokers as 1, e: negative family history was defined as 0, positive family as 1, f: healthy controls were defined as 0, SLE patients were defined as 1.
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Arthritis Research & Therapy

ISSN: 1478-6362

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