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Table 4 Differences in vascular parameters between SLE patients with and without hypertension

From: Small artery elasticity is decreased in patients with systemic lupus erythematosus without increased intima media thickness

 

CTL (n= 0)

SLE - hypertension

(n= 21)

SLE + hypertension

(n= 9)

SAE, ml/mmHg × 100

8.1 ± 2.6

6.4 ± 2.1*

6.4 ± 4.0

AF, AU

1.9 ± 0.4

2.1 ± 0.5*

2.2 ± 0.6

IMT, mm

   

   Mean Maximum

0.72 (0.69 to 0.87)

0.70 (0.68 to 0.76)

0.73 (0.60 to 0.98)

   Mean

0.64 (0.59 to 0.70)

0.61 (0.58 to 0.65)

0.62 (0.55 to 0.81)

VCAM-1, ng/ml

371 ± 101

534 ± 159**

578 ± 182**

vWf, %

67 (46 to 88)

123 (89 to 189)**

156 (83 to 397)**

TM, ng/ml

1.6 (1.2 to 1.7)

1.8 (1.4 to 2.6)

1.3 (0.6 to 1.8)

  1. Unless stated otherwise, data are expressed as mean ± standard deviation when normally distributed and as median (interquartile range) when non-normally distributed. AF, autofluorescence; AU, arbitrary units; CTL, healthy controls; MT, intima media thickness; SAE, small artery elasticity; SLE, SLE patients; TM, thrombomodulin; VCAM-1, vascular cell adhesion molecule-1; vWf, von Willebrand factor. Patients versus controls: * P ≤ 0.05, ** P ≤ 0.01. There were no significant differences between SLE patients without hypertension and SLE patients with hypertension.