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Supplementary Table 2 Demographics and clinical features of 576 SLE patients

From: Genetic linkage and transmission disequilibrium of marker haplotypes at chromosome 1q41 in human systemic lupus erythematosus

  Sibpair Trio
Number of families 210 122
Number of affected individuals (sex, F:M) 440:10 123:0
Family ethnicity   
   White 78 96
   African-American 10 1
   Hispanic 7 1
   Asian 2 1
   Mixed heritage 3 1
Laboratory/clinical features (%)   
   ANA positive 98 97
   Anti-dsDNA positive 46 72***
   Arthritis 85 84
   Skin involvement 92 82**
   Pleuritis 53 45*
   Hematologic 48 72***
   Renal disease 33 53***
   CNS lupus 25 15**
   Pericarditis 19 20
  1. Data represent the percentage of SLE patients having the indicated laboratory/clinical features at any time during the course of their disease. Differences in the clinical features between the trio and sibpair familiy collections were determined using generalized estimating equations to adjust for intrafamilial correlation within the sibpair families [S15]. ***P <0.0001, **P <0.01, *P <0.05. ANA = antinuclear antibodies; CNS = central nervous system