Image co-registration in rheumatoid arthritis. Images from a patient with early rheumatoid arthritis, obtained using three different modalities. (a) Conventional radiography. (b) Coronal short tau inversion recovery (STIR) sequence. (d) Axial gadopentate dimeglumine enhanced fat-suppressed T1-weighted image. (c, e) Multipinhole single-photon-emission computed tomography (MPH-SPECT) images overlaid with appropriate magnetic resonance images (MRI). The overlaid MPH-SPECT images display areas of focally increased bone metabolism in the second and third proximal interphalangeal and metacarpalphalangeal joints (corresponding to the boxed area in (a), which showed no bony pathologies on MRI. Reproduced with permission from .