From: Matrix metalloproteinase-8 deficiency increases joint inflammation and bone erosion in the K/BxN serum-transfer arthritis model
Mice
Control versus rheumatoid arthritis
FDR <0.05
FDR <0.01
Pcorr<0.05
Mmp8 +/+
2,996
994
77
Mmp8 -/-
3,407
1,046
52
Mmp8+/+ and Mmp8-/-
2,136
660
40
Mmp8+/+ exclusive
860
334
37
Mmp8-/- exclusive
1,271
386
12