Figure 1
From: Dual role of interleukin-17 in pannus growth and osteoclastogenesis in rheumatoid arthritis
Effect of interleukin (IL)-17 on the production of (A) IL-6 (A) and (B) prostaglandin E2 (PGE2) by the synovial tissue (ST)-derived inflammatory cells. Cells were incubated in the absence or presence of increasing concentrations of IL-17 (0 to 100 ng/ml) for 3 weeks. IL-6 (n = 7) and PGE2 (n = 3) in the culture supernatants were measured by enzyme-linked immunosorbent assay as described in Materials and methods.