MIG/CXCL9, IP-10/CXCL10, and CXCL16 are overexpressed in SSc serum. The amounts of MIG/CXCL9 (A), IP-10/CXCL10 (B), and CXCL16 (C) were determined in normal and SSc serum by ELISA. Means are given with SEM. Differences were determined using the Student's t-test and P-values less than 0.05 were significant. n = number of patients.