Figure 2

K_2P5.1 expression on CD4⁺ T lymphocytes correlates with disease activity parameters. A) Expression levels of K_2P5.1 (Δct values) and DAS28 scores are shown for 58 individual patients for CD4⁺ (left side) and CD8⁺ (right side) T lymphocytes. Note that the x-axis (Δct values) is logarithmic scale and that lower Δct values mean higher gene expression. B) Δct values for K_2P5.1 and ESR rates (mm/h) are depicted for CD4⁺ (left side) and CD8⁺ (right side) T lymphocytes. C) Δct values for K_2P5.1 and CRP levels (mg/dl) are shown for CD4⁺ (left side) and CD8⁺ (right side) T lymphocytes. D) The correlation coefficient for K_2P5.1 and DAS28, ESR or CRP is shown for CD4⁺ and CD8⁺ T lymphocytes. E) K_2P5.1 expression levels on CD4⁺ T cells are shown on clinically defined patient subgroups as stated in the Material and Methods section.