Figure 2From: The role of the Notch pathway in healthy and osteoarthritic articular cartilage: from experimental models to ex vivo studiesCanonical and non-canonical (Abl) Notch signaling pathways. A, co-activator; CSL, CBF, Su(H), Lag3; DSL, Delta, Serrate, Lag2; R, co-repressor; S1, S2, S3 and S4, Notch cleavage sites in the canonical signaling pathway; TACE, tumor necrosis factor alpha converting enzyme.Back to article page