| CCR4+/CCR6+ Th/Th | CCR4+/CCR6+ Th/T | CCR4+/CCR6+ Th/L | Treg/Th | Treg/T | Treg/L | Fox-P3+/CD4+CD25+ |
---|
ASp | 9.81 ± 0.62 | 7.69 ± 0.63 | 4.24 ± 0.56 | 2.82 ± 0.24 | 2.12 ± 0.23 | 1.23 ± 0.13 | 22.23 ± 5.13 |
HD1 | 5.51 ± 0.59 | 3.53 ± 0.56 | 2.24 ± 0.48 | 5.27 ± 0.28 | 4.13 ± 0.26 | 2.54 ± 0.15 | 32.54 ± 7.05 |
HD2 | 5.34 ± 0.52 | 3.33 ± 0.45 | 2.17 ± 0.37 | 5.31 ± 0.23 | 4.21 ± 0.19 | 2.64 ± 0.18 | 34.92 ± 6.71 |
- Data presented as the percentage mean ± standard deviation. The differences for all percentages between patients with ankylosing spondylitis (ASp) and either HLA-B27-negative healthy donors (HD1) or HLA-B27-positive healthy donors (HD2) were significant (P < 0.001, according to a two-tailed significant level of 0.05). There were no significant differences between HD1 and HD2 (P > 0.05). Th, CD4+ T-helper cells; T, T lymphocytes; L, lymphocytes; Treg, forkhead box P3-positive regulatory T cells.