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Table 3 Percentages of CCR4+/6+ Th and Treg cells in appropriate cell subsets

From: Reduced immunomodulation potential of bone marrow-derived mesenchymal stem cells induced CCR4+CCR6+Th/Treg cell subset imbalance in ankylosing spondylitis

  CCR4+/CCR6+ Th/Th CCR4+/CCR6+ Th/T CCR4+/CCR6+ Th/L Treg/Th Treg/T Treg/L Fox-P3+/CD4+CD25+
ASp 9.81 ± 0.62 7.69 ± 0.63 4.24 ± 0.56 2.82 ± 0.24 2.12 ± 0.23 1.23 ± 0.13 22.23 ± 5.13
HD1 5.51 ± 0.59 3.53 ± 0.56 2.24 ± 0.48 5.27 ± 0.28 4.13 ± 0.26 2.54 ± 0.15 32.54 ± 7.05
HD2 5.34 ± 0.52 3.33 ± 0.45 2.17 ± 0.37 5.31 ± 0.23 4.21 ± 0.19 2.64 ± 0.18 34.92 ± 6.71
  1. Data presented as the percentage mean ± standard deviation. The differences for all percentages between patients with ankylosing spondylitis (ASp) and either HLA-B27-negative healthy donors (HD1) or HLA-B27-positive healthy donors (HD2) were significant (P < 0.001, according to a two-tailed significant level of 0.05). There were no significant differences between HD1 and HD2 (P > 0.05). Th, CD4+ T-helper cells; T, T lymphocytes; L, lymphocytes; Treg, forkhead box P3-positive regulatory T cells.