Figure 8From: Intraarticular injection of hyaluronan prevents cartilage erosion, periarticular fibrosis and mechanical allodynia and normalizes stance time in murine knee osteoarthritisFibrotic tissue changes around the lateral tibial plateau associated with experimental murine osteoarthritis (OA). Typical sections from (a and b) the treadmill-only group and (c and d) the OA group are shown stained with (a and c) Safranin O or (b and d) antibodies to type I collagen. Black arrows indicate Safranin O-deficient tissue populated with collagen type I-positive cells (c and d), respectively. PO, periosteum; GP, growth plate; TP, tibial plateau; SY, synovium.Back to article page