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Figure 8 | Arthritis Research & Therapy

Figure 8

From: Intraarticular injection of hyaluronan prevents cartilage erosion, periarticular fibrosis and mechanical allodynia and normalizes stance time in murine knee osteoarthritis

Figure 8

Fibrotic tissue changes around the lateral tibial plateau associated with experimental murine osteoarthritis (OA). Typical sections from (a and b) the treadmill-only group and (c and d) the OA group are shown stained with (a and c) Safranin O or (b and d) antibodies to type I collagen. Black arrows indicate Safranin O-deficient tissue populated with collagen type I-positive cells (c and d), respectively. PO, periosteum; GP, growth plate; TP, tibial plateau; SY, synovium.

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