The role of synovial fluid markers of catabolism and anabolism in osteoarthritis, rheumatoid arthritis and asymptomatic organ donors

Table 4 Spearman rank correlation coefficients for OA study population^a

	IL-1	IL-6	IL-8	IL-11	LIF	Osteocalcin	COMP	OP-1
IL-1	1.0000
IL-6	ρ = -0.3386 P = 0.186	1.0000
IL-8	ρ = 0.6233 P = 0.001	ρ = -0.3709 P = 0.0095	1.0000
IL-11	ρ = -0.2312 P = 0.1136	ρ = 0.5384 P = 0.0001	ρ = -0.2365 P = 0.1056	1.0000
LIF	ρ = -0.5241 P = 0.0001	ρ = 0.7165 P = 0.001	ρ = -0.4012 P = 0.0047	ρ = 0.4352 P = 0.0020	1.0000
Osteocalcin	ρ = -0.3432 P = 0.0169	ρ = 0.4538 P = 0.0012	ρ = -0.4456 P = 0.0015	ρ = 0.3094 P = 0.0324	ρ = 0.5043 P = 0.0003	1.0000
COMP	ρ = 0.0807 P = 0.5856	ρ = 0.0294 P = 0.8427	ρ = -0.1522 P = 0.3018	ρ = 0.1623 P = 0.2704	ρ = -0.0854 P = 0.5639	ρ = 0.1526 P = 0.3004	1.0000
OP-1	ρ = 0.1038 P = 0.4828	ρ = 0.0730 P = 0.6222	ρ = -0.0529 P = 0.7211	ρ = 0.2028 P = 0.1669	ρ = 0.1003 P = 0.4975	ρ = 0.2084 P = 0.1552	ρ = 0.1193 P = 0.4193	1.000

^a OA, osteoarthritis; IL, interleukin; LIF, leukemia-inhibitory factor; COMP, cartilage oligomeric protein; OP-1, osteogenic protein 1. Spearman's rank correlation coefficients (IL-1, IL-6, IL-8, IL-11, LIF, osteocalcin, COMP and OP-1) for the OA cohort are expressed as Spearman's ρ and P values. A total of 45 OA patients were sampled, six male and thirty-nine female.

ISSN: 1478-6362