Skip to main content


Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Figure 2 | Arthritis Research & Therapy

Figure 2

From: Cystatin C influences the autoimmune but not inflammatory response to cartilage type II collagen leading to chronic arthritis development

Figure 2

The anti-CII IgG antibody titers are elevated in the cystatin C-deficient mice. Mice were bled at Day 34 (A) before boost immunization with CII/IFA, and at the end of the experiment at Day 115 (B). There was a statistically significant difference between the antibody production of cystatin C-deficient mice (Cyst C -/-) and the wild type controls (Cyst C +/+) at Day 115. ** P-value < 0.01 as tested with Mann-Whitney.

Back to article page