Figure 3
Decrease in the expressions of three DNA repair genes. The expression levels of (a) excision repair cross-complementing (ERCC)2, (b) ERCC5, and (c) X-ray repair cross-complementing (XRCC)6 in peripheral blood of 21 patients with systemic lupus erythematosus (SLE) and 45 healthy individuals (HI) are shown. All data represent microarray data with the expression values of log2(sample/reference). *P < 0.05, **P < 0.01, ***P < 0.001 (unpaired Mann-Whitney test) for 21 SLE patients versus 45 HI. Boxes contain the 50% of values falling between the 25th and 75th percentiles, the horizontal line within the box represents the median value, and the whiskers are the lines that extended from the box to the highest and lowest values, excluding outliers.