Hyaluronan modulates accumulation of hypoxia-inducible factor-1 alpha, inducible nitric oxide synthase, and matrix metalloproteinase-3 in the synovium of rat adjuvant-induced arthritis model

Table 2 Association of pain withdrawal threshold with the immunoreactivity results given as gamma values

Correlations were analyzed by Pearson correlation coefficients. ^aP < 0.01; ^bP < 0.05.
1D, one dose; 3D, three doses; 3D6d, follow-up at the 6th day after three doses; HIF-1α, hypoxia-inducible factor-1-alpha; iNOS, inducible nitric oxide synthase; MMP3, matrix metalloproteinase-3.