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Table 2 Development of ATI by MTX treatment in RA and SpA patientsa

From: Antibodies toward infliximab are associated with low infliximab concentration at treatment initiation and poor infliximab maintenance in rheumatic diseases

 

RA (n= 17)

SpA (n= 91)

MTX treatment

ATIpos

ATIneg

Pvalue

ATIpos

ATIneg

Pvalue

MTX+

3

6

 

0

25

 

MTX-

4

4

0.8

14

52

0.03

  1. aATI: antibodies toward infliximab; ATIpos: ATI detected at least once during follow-up; ATIneg: ATI not detected; RA: rheumatoid arthritis; SpA: spondyloarthritis; MTX: methotrexate. Data represent number of patients in each category.