Table 5 Characteristics of the 77 RA patients stratified by IL-6 -174G/C SNPa
Characteristics | GG | GC | CC | P value |
|---|---|---|---|---|
Mean age, years (± SD) | 57.5 ± 13.5 | 51.1 ± 16.1 | 61.4 ± 11.9 | NS |
Mean disease duration, months (± SD) | 117.6 ± 74.4 | 144 ± 129.6 | 45.6 ± 19.2 | P = 0.01; GG vs. CC |
RF-positive, n (%) | 39 (81.2) | 17 (70.8) | 4 (80) | NS |
ACPA-positive, n (%) | 40 (83.3) | 16 (66.6) | 3 (60) | NS |
Mean DAS28 (± SD) | 5.3 ± 1.2 | 4.8 ± 1.3 | 4.7 ± 0.8 | NS |
Mean HAQ score (± SD) | 1.3 ± 0.7 | 1.3 ± 0.9 | 1.3 ± 0.7 | NS |
Mean overall patient TES (± SD) | 36.2 ± 20.4 | 27 ± 21.8 | 35.4 ± 28.4 | NS |
Mean MCP TES (± SD) | 14 ± 8.0 | 12 ± 8.4 | 12.4 ± 9 | NS |
Mean PIP TES (± SD) | 10.3 ± 7.9 | 7.5 ± 7.6 | 13 ± 11.2 | NS |
Mean MTP TES (± SD) | 11.9 ± 7.7 | 7.4 ± 8.1 | 10 ± 8.8 | P = 0.007; GC vs. CC |