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Table 1 Five anti-RNAP III positive cases that were not classified as SSc at their initial visit

From: Atypical clinical presentation of a subset of patients with anti-RNA polymerase III - non-scleroderma cases associated with dominant RNA polymerase I reactivity and nucleolar staining

  1 2 3 4 5
  Initial f/u Initial f/u    
Diagnosis Vasculitis? SSc Poly
-arthritis
SSc Sine SSc? ILD Sjögren's syndrome
Race/gender WF Mixed F WF WF WF
Anti-RNAP III
ELISA (u)
16 NA 99 127 8 15
to 47
42
Proximal scleroderma N Y
< 10 mo
N Y
3 mo
N N N
Sclerodactyly N Y
< 10 mo
N Y
2 mo
N N N
Pitting scar N N N N N N N
ILD N N N N N Y N
Raynaud's phenomenon N ? N Y
6 mo
Y
For 10 y
N N
Other   Renal crisis
10 mo
  Flex.cont
PH
ARF (TMA), DCM   
  1. ARF, acute renal failure; DCM, dilated cardiomyopathy; W, white; F, female; Flex cont, flexion contracture; f/u, follow up; ILD, interstitial lung disease; N, no; NA, not available; PH, pulmonary hypertension; SSc, systemic sclerosis, scleroderma; TMA, thrombotic microangiopathy; Y, yes